加替沙星水合物CAS: 180200-66-2分析纯 工业级 科研试剂 全国送货 一瓶起售
更新时间：2025-08-20 17:12:41
价格：请来电询价
化学式:C19H24FN3O5
分子量:393.42
沸点:684℃
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详细介绍
| 中文名 | 水合加替沙星 |
| 英文名 | Gatifloxacin ses |
| 别名 | 水合加替沙星 加替沙星水合物 加替沙星羧酸乙酯 1-环丙基-6-氟-4-氧代-8-甲氧基-7-(3-甲基 1-环丙基-6-氟-8-甲氧基-7-(3-甲基哌嗪-1-基)-4-氧代3-喹啉羧酸 1-环丙基-6-氟-8-甲氧基-7-(3-甲基哌嗪-1-基)-4-氧代-3-喹啉羧酸 1-环丙基-6-氟-8-甲氧基-7-(3-甲基-1- 哌嗪)-4-氧代-喹啉-3-羧酸 1-环丙基-6-氟-8-甲氧基-7-(3-甲基哌嗪-1-基)-4-氧代-1,4-二氢3-喹啉羧酸 |
| 英文别名 | (+-)-1-C Gatifloxacin (300 mg) Gatifloxacin Monohydrate Gatifloxacin ses Gatifloxacin formic acid ethyl ester 1-cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-ic acid Gatifloxcin 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(3-Methyl-1-piperazinyl)-4-oxo-3-ic acid 1-Cyclopropyl-6-fluoro-8-Methoxy-7-(3-Methylpiperazin-1-yl)-4-oxo-1,4-dihydroxylic acid ses |
| CAS | 180200-66-2 |
| EINECS | 672-577-2 |
| 化学式 | C19H24FN3O5 |
| 分子量 | 393.42 |
| 沸点 | 684℃ |
| 溶解度 | 溶于1N NaOH，浓度为10mg/ml |
| 存储条件 | Keep in dark place,Inert atmosphere,2-8°C |
| 外观 | 整洁 |
| BRN | 14390028 |
| 体外研究 | Gatifloxacin ses is against S. aureus MS5935 topoisomerase IV, E. coli NIHJ JC-2 DNA gyrase and HeLa cell topoisomerase II with IC 50 values of 13.8 μg/ml, 0.109 μg/ml, and 265 μg/ml, respectively.Gatifloxacin ses is against S. aureus MS5935 topoisomerase IV, E. coli NIHJ JC-2 DNA gyrase and HeLa cell topoisomerase II with MIC values of 0.05 μg/ml, 0.0063 μg/ml, and 122 μg/ml, respectively.Gatifloxacin ses exhibits antibacterial activities for wild-type strains (MS5935, MS5952, MR5867 and MR6009) the first-, second-, third-, and fourth-step mutants with MIC values of 0.05 to 0.10 μg/ml, 0.20 μg/ml, 1.56 to 3.13 μg/ml, 1.56 to 6.25 μg/ml, and 50 to 200 μg/ml, respectively. Gatifloxacin ses displays the most potent activity against the second- and third-step mutants (MS5952, MR5867 and MR6009) except for the second-step mutant of strain MS5935.Gatifloxacin ses has potent activity against norA transformant NY12 (MIC, 0.39 μg/ml).Gatifloxacin ses (20-100 μM; 72 hours) significantly decreases insulin content to 60% at Day 1, and continues to be reduced to 50.1% and 44.7% at Day 3 by 20 μM and 100 μM Gatifloxacin ses, respectively. |
| 危险品标志 | Xn - 有害物品 |
| 风险术语 | 20/21/22 - 吸入、皮肤接触及吞食有害。 |
| 安全术语 | 36/37 - 穿戴适当的防护服和手套。 |
| WGK Germany | 1 |
| RTECS | VB1983600 |
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